Gender Difference In Autoimmune Disease Explained By Newly Discovered B Cells

August 8th, 2011

Researchers at National Jewish Health have discovered a type of cell that may contribute to autoimmune disease. The findings also suggest why diseases such as lupus, multiple sclerosis and rheumatoid arthritis strike women more frequently than men. The cells, a subset of immune-system B cells, make autoantibodies, which bind to and attack the body’s own tissue. The researchers report in the journal Blood, that they found higher levels of these cells in elderly female mice, young and old mice prone to autoimmune disease, and humans with autoimmune diseases…

Review Of Atrial Fibrillation Guidelines Announced By ESC

August 8th, 2011

The Guidelines Department of the European Society of Cardiology has issued the following statement : “The European Society of Cardiology (ESC) is aware of the early termination of the PALLAS trial (a randomised dronedarone versus placebo outcomes study in patients with permanent atrial fibrillation and cardiovascular risk) because of adverse outcomes associated with dronedarone…

Review Of Atrial Fibrillation Guidelines Announced By ESC

August 8th, 2011

The Guidelines Department of the European Society of Cardiology has issued the following statement : “The European Society of Cardiology (ESC) is aware of the early termination of the PALLAS trial (a randomised dronedarone versus placebo outcomes study in patients with permanent atrial fibrillation and cardiovascular risk) because of adverse outcomes associated with dronedarone…

Natural Food Preservative That Kills Food-Borne Bacteria

August 8th, 2011

University of Minnesota researchers have discovered and received a patent for a naturally occurring lantibiotic – a peptide produced by a harmless bacteria – that could be added to food to kill harmful bacteria like salmonella, E. coli and listeria. The U of M lantibiotic is the first natural preservative found to kill gram-negative bacteria, typically the harmful kind. “It’s aimed at protecting foods from a broad range of bugs that cause disease,” said Dan O’Sullivan, a professor of food science and nutrition in the university’s College of Food, Agricultural and Natural Resource Sciences…

Natural Food Preservative That Kills Food-Borne Bacteria

August 8th, 2011

University of Minnesota researchers have discovered and received a patent for a naturally occurring lantibiotic – a peptide produced by a harmless bacteria – that could be added to food to kill harmful bacteria like salmonella, E. coli and listeria. The U of M lantibiotic is the first natural preservative found to kill gram-negative bacteria, typically the harmful kind. “It’s aimed at protecting foods from a broad range of bugs that cause disease,” said Dan O’Sullivan, a professor of food science and nutrition in the university’s College of Food, Agricultural and Natural Resource Sciences…

Loss Of A Gene Regulator Is Crucial For A Rare Type Of Skin Cancer

August 8th, 2011

Malignant Sezary syndrome is characterized by the reproduction of a special type of white blood cell in the skin of male and female patients. In contrast to most other skin lymphomas, patients with Sezary syndrome manifest not only skin contamination but also contamination of blood and lymph nodes by degenerate T cells even at the onset of the disease. The researchers investigated highly purified tumor cells from patients with Sezary syndrome using modern, high-resolution genetic procedures (the so-called array comparative genomic hybridization technique) for hitherto unknown genetic changes…

Loss Of A Gene Regulator Is Crucial For A Rare Type Of Skin Cancer

August 8th, 2011

Malignant Sezary syndrome is characterized by the reproduction of a special type of white blood cell in the skin of male and female patients. In contrast to most other skin lymphomas, patients with Sezary syndrome manifest not only skin contamination but also contamination of blood and lymph nodes by degenerate T cells even at the onset of the disease. The researchers investigated highly purified tumor cells from patients with Sezary syndrome using modern, high-resolution genetic procedures (the so-called array comparative genomic hybridization technique) for hitherto unknown genetic changes…

Discovery Of Potential New Eye Tumor Treatment

August 8th, 2011

New research from a team including several Carnegie scientists demonstrates that a specific small segment of RNA could play a key role in the growth of a type of malignant childhood eye tumor called retinoblastoma. The tumor is associated with mutations of a protein called Rb, or retinoblastoma protein. Dysfunctional Rb is also involved with other types of cancers, including lung, brain, breast and bone…

Discovery Of Potential New Eye Tumor Treatment

August 8th, 2011

New research from a team including several Carnegie scientists demonstrates that a specific small segment of RNA could play a key role in the growth of a type of malignant childhood eye tumor called retinoblastoma. The tumor is associated with mutations of a protein called Rb, or retinoblastoma protein. Dysfunctional Rb is also involved with other types of cancers, including lung, brain, breast and bone…

Fully Cooked Food Supplement

August 8th, 2011

U.S. Department of Agriculture (USDA) scientists have developed a fully cooked food-aid product called Instant Corn Soy Blend that supplements meals, particularly for young children. The work was led by food technologist Charles Onwulata at the Agricultural Research Service (ARS) Dairy Processing and Products Research Unit at the agency’s Eastern Regional Research Center (ERRC) in Wyndmoor, Pa. ARS is USDA’s chief intramural scientific research agency, and this research supports the USDA priority of promoting international food security…